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Prepare the horseradish aioli: In a small bowl, whisk together mayonnaise, prepared horseradish, Dijon mustard, lemon juice, a pinch of salt, and a pinch of black pepper until well combined. Cover and refrigerate until ready to use.
Prepare the caramelized onions: In a large skillet, melt butter and olive oil over medium-low heat. Add the sliced yellow onion and cook slowly, stirring occasionally, for 20-25 minutes until deeply golden brown and caramelized. Stir in the chopped fresh thyme during the last 5 minutes of cooking. Season with salt and black pepper. Remove from heat and set aside.
While the onions cook, prepare the au jus: In a saucepan over medium heat, combine beef broth, soy sauce, Worcestershire sauce, garlic powder, onion powder, black pepper, and chopped fresh rosemary. Stir and bring to a simmer. Reduce heat to low and keep warm.
Preheat the oven to 375°F. Carefully slice the brioche slider buns in half horizontally. Arrange the bottom halves of the buns on a large baking sheet.
Spread a thin layer of roasted garlic spread on the cut side of each bottom bun. Lightly toast in the preheated oven for 2-3 minutes, just until fragrant and slightly golden. Remove from oven.
Layer each bottom bun half with a portion of thinly sliced roast beef, a spoonful of the caramelized onions, and 1-2 slices of Swiss cheese. Place the top bun halves on top of the assembled sliders.
Bake the sliders in the preheated oven for 10-15 minutes, or until the Swiss cheese is bubbly and melted and the buns are lightly toasted and golden.
Carefully remove the sliders from the oven. Serve immediately with the warm au jus for dipping and a side of the prepared horseradish aioli.

Prepare the horseradish aioli: In a small bowl, whisk together mayonnaise, prepared horseradish, Dijon mustard, lemon juice, a pinch of salt, and a pinch of black pepper until well combined. Cover and refrigerate until ready to use.
Prepare the caramelized onions: In a large skillet, melt butter and olive oil over medium-low heat. Add the sliced yellow onion and cook slowly, stirring occasionally, for 20-25 minutes until deeply golden brown and caramelized. Stir in the chopped fresh thyme during the last 5 minutes of cooking. Season with salt and black pepper. Remove from heat and set aside.
While the onions cook, prepare the au jus: In a saucepan over medium heat, combine beef broth, soy sauce, Worcestershire sauce, garlic powder, onion powder, black pepper, and chopped fresh rosemary. Stir and bring to a simmer. Reduce heat to low and keep warm.
Preheat the oven to 375°F. Carefully slice the brioche slider buns in half horizontally. Arrange the bottom halves of the buns on a large baking sheet.
Spread a thin layer of roasted garlic spread on the cut side of each bottom bun. Lightly toast in the preheated oven for 2-3 minutes, just until fragrant and slightly golden. Remove from oven.
Layer each bottom bun half with a portion of thinly sliced roast beef, a spoonful of the caramelized onions, and 1-2 slices of Swiss cheese. Place the top bun halves on top of the assembled sliders.
Bake the sliders in the preheated oven for 10-15 minutes, or until the Swiss cheese is bubbly and melted and the buns are lightly toasted and golden.
Carefully remove the sliders from the oven. Serve immediately with the warm au jus for dipping and a side of the prepared horseradish aioli.